AI-backed genomic and clinical data company Sema4 announced this week it would exit the reproductive health testing business, shut down its lab in Stamford, Connecticut, and lay off about 500 employees.

The company said it would complete its departure from the segment in the first quarter next year. It will now employ about 1,100 workers. According to a WARN Act Notice filed in Connecticut, the cuts affect 206 employees who report to its headquarters in Stamford, 227 who work in the Stamford lab and 15 from its Branford lab. 

The latest layoffs come months after Sema4 cut around 250 staffers, then around 13% of its workforce, as part of another restructuring. Combined with layoffs from earlier this year, Sema4 said in August it had cut about 30% of its jobs from its legacy business.

By eliminating the reproductive health segment, the company will double down on its GeneDx exome and

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When your thoughts feel like a tornado, it’s hard to do stuff like plan healthy meals, or schedule gym time.

Never mind falling asleep at a decent hour the night before so you have the energy to actually DO these things.

Seems like an unlikely hero—but your phone might help.

Specifically, via stress management apps.

Stress management apps promise to help you manage your thoughts, regulate your emotions, and ease tension and restlessness from your body.

And in turn, better recovery from stress “fills up your tank,” making it easier for you to eat mindfully, find time to exercise, and feel like you have the capacity to take on new challenges.

A graphic showing how to keep your recovery tank full. The illustration shows a water tank with a tap pouring water in, and a tap on the tank itself that lets water out. The tap that fills the tank is recovery, which includes elements like: good nutrition, regular sleep, gentle movement, fulfilling activity, social connections, positive emotions, time in nature, and mindfulness. The tap that empties the tank is stress, which includes elements like poor nutrition, low energy intake, intense exercise, work stress, relationship stress, caregiving, financial stress, loneliness, negative emotions, environmental stress, alcohol and drug use, illness, and injury.

In the following article, we’ll discuss how apps for stress management and anxiety might help you do that. You’ll discover:

  • What stress apps are, and how they work
  • Who’s most likely to benefit from these apps
  • Which stress management
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Reviewed by Gabrielle Fundaro, PhD, CISSN, CHC


“I can’t go out tonight, I’m… busy.”

If you struggle with gut health problems, you know this line is often code for one—or all—of the following:

“I have to stay close to the bathroom.”

“I can’t wear real pants right now.”

“My farts might kill you.”

Digestive symptoms like gas, bloating, indigestion, and toilet troubles are common—and can be extremely disruptive (and not just to your social life).

But if you’re frequently plagued by these issues, all you really want to know is:

What will actually help my belly feel better??!

A lot, actually.

In the following story, you’ll discover:

  • How stress, exercise, and many other factors affect your gut health and microbiome
  • How to restore gut health after taking antibiotics
  • Whether you’re the kind of person who could benefit from extra fiber
  • If fermented foods live up to their hype
  • Which
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“I wish I was the kind of person that loves to exercise… I’m just not that guy.”

My friend Dave takes a sip from his perfectly poured pint, while explaining his reluctance to exercise.

“I’m the guy who’s really into beer,” he adds. “I have no interest in exercise. Beer is my thing. That’s who I am.”

Dave, like lots of people, knows exercise is something he “should” do. But it holds no appeal.

Going for a run—and actually enjoying it? Unfathomable to him. The gym? Forget it.

Coaches, doctors, and fitness enthusiasts love to espouse the benefits of physical activity: It makes you feel good! It’s rewarding! It’s necessary! 

Yet, like a triple hopped IPA, exercise can be an acquired taste. Some people love it at first sip, some learn to love it, and others just plain don’t like it.

And that’s okay.

Disliking exercise isn’t some kind of

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It was 2008 when Dom Matteo stepped on the scale and saw the number 300.

That’s when he stopped weighing himself.

In 2009, Stephen Box decided, ‘I’m just going to be fat forever. Whatever.’

After diligently trying to lose fat for thirty years, Katey Caswell was still morbidly obese. She wondered, ‘Is anything ever going to work?’

This isn’t a story about three people who gave up.

Rather, it’s about three people who kept going—overcoming the nearly universal setbacks and challenges during major body transformations.

Not only did all three eventually lose 80-plus pounds apiece, but they also changed in other ways: Dom, Stephen, and Katey have all become certified health and nutrition coaches who now help others eat, move, and live better.

In this story, you’ll discover their top mindset strategies for persevering when fat loss feels impossible (or at least just very frustrating).

Caveat: Not every strategy will

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